Bevacizumab 400mg price in India, Uses and Side Effects

Bevacizumab 400mg Injection is an anticancer injection. It’s used to treat several types of cancer, like colon and rectal cancer, non-small cell lung cancer, kidney cancer, brain tumours, ovarian and cervical cancer, and other cancers. It aids in the prevention of the formation of new blood vessels that feed tumours as well as tumour growth.

Bevacizumab 400mg Injection is a very effective medicine when used first-line together with other cancer medicines. It is given in the form of an infusion and inserted through a small needle into a vein or through a port, which is a device placed under your skin. It is given through a small needle in your vein or a port, which is a device placed under your skin.

Your doctor will decide the dose and duration of treatment, as well as look for signs of an infusion reaction, such as high blood pressure and difficulty breathing. You can continue to take this medicine as long as your disease is under control and the side effects are tolerable.

Your doctor will decide whether you should discontinue using it or not. While taking this medication, you may be advised to monitor your blood pressure and protein levels in your urine.

Bevacizumab Injection Benefits

Colon and rectum cancer

Colon and rectum cancer, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from either the colon or the rectum of the large intestine. Symptoms of this type of cancer include blood in the stool, changes in bowel movements, weight loss, and fatigue.

Bevacizumab 400mg injections both treat and reduce the risk of developing additional cancerous growths (polyps) and bowel cancer. It kills or slows the growth of cancer cells while also preventing their multiplication. It is a highly effective but extremely toxic medication, and you should discuss the risks and benefits with your doctor.

Non small cell lung cancer

Non-small cell lung cancer is one of the most common types of lung cancer, affecting both smokers and nonsmokers. The injection is used to treat non-small cell lung cancer and can be used alone or in conjunction with other medications. It is a potent and highly toxic medication, and you should consult your doctor about the risks and benefits. While undergoing this treatment, you should avoid alcohol, smoking, and drink plenty of water to stay hydrated.

Kidney cancer

Bevacizumab 400mg injection is used to treat kidney cancer and its symptoms, which include blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, and so on. It slows cancer growth and prevents cancer cells from multiplying. This prevents cancer from spreading to other unaffected areas. To recover, you must strictly follow your doctor’s instructions.

Brain cancer

A brain tumour is a malignant (cancerous) or non-cancerous mass or collection of cells (benign). Bevacizumab can kill or slow the growth of cancer cells while also preventing cancer cell multiplication. If you have any concerns, speak with your doctor.

Ovarian cancer

Ovarian cancer is a type of cancer that begins in the female reproductive organs (ovaries). Typically, it is detected late in its progression and can be fatal. Typically, it spreads to the pelvis and stomach.

Bevacizumab 400mg injections kill or slow the growth of cancer cells while also preventing their multiplication. It is a useful medication, but it has some side effects that may be bothersome. As a result, you should talk to your doctor about the risks and benefits.

Cervical cancer

Bevacizumab 400mg injection is an anti-cancer medication used to kill cancerous cells in cervical cancer, which develops in a female’s cervix. The affected female may experience symptoms such as abnormal bleeding, foul-smelling vaginal discharge, lower back pain, or none at all. It has a lot of side effects, and you should talk to your doctor about the risks and benefits before starting treatment with this medicine.

References:

1. Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 24/05/2022], https://www.medicines.org.uk/emc/files/pil.3885.pdf
2. Roche Group, U.S FDA, [Revised on Jan 2021][ Accessed on 21/11/2022], https://www.gene.com/download/pdf/avastin_prescribing.pdf
3.  Roche Group,Bevacizumab Injection, Indication,[Revised on 2020] [Accessed on 21/11/2022] https://www.avastin.com/patient/mcrc.html

Bevacizumab injection uses

• Cancer of colon and rectum
• Non-small cell lung cancer (NSCLC)
• Kidney cancer
• Brain tumour
• Ovarian cancer
• Cervical cancer

How Bevacizumab injection works

Bevacizumab 400mg injection is an anti-angiogenic medicaiton. It works by inhibiting a protein known as vascular endothelial growth factor (VEGF). This prevents the formation of blood vessels, which transport oxygen and nutrients to cancerous cells.

Bevacizumab Injection uses in Covid

Bevacizumab is a VEGF (Vascular Endothelial Growth Factor) inhibitor drug. The drug is commonly used in clinical oncology, and it’s a promising treatment for ALI and ARDS in COVID-19 since it suppresses pulmonary emphysema. An anti-VEGF medicine called bevacizumab could be used to treat ALI or ARDS caused by COVID-19. It is a long-acting humanized monoclonal antibody.

Bevacizumab mechanism of action

Bevacizumab works by selectively bindling circulating VEGF and inhibiting its binding to cell surface receptors. This inhibition reduces the microvascular growth of tumour blood vessels, limiting blood supply to tumour tissues.

The most common side effects of Bevacizumab Injection

The most common side effects of this medicine are rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has the potential to reduce wound healing ability. Aside from that, it increases your risk of bleeding, so if you notice any unusual bleeding or bleeding, consult your doctor right away.

If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know all medications you are using.

Bevacizumab side effects

• Rectal bleeding
• Taste change
• Headache
• Nosebleeds
• Back pain
• Dry skin
• High blood pressure
• Protein in urine
• Inflammation of the nose

Bevacizumab 400mg brands in India